MINNELIDE/TRIPTOLIDE IMPAIRS MITOCHONDRIAL FUNCTION BY REGULATING SIRT3 IN P53-DEPENDENT MANNER IN NON-SMALL CELL LUNG CANCER.

Minnelide/Triptolide Impairs Mitochondrial Function by Regulating SIRT3 in P53-Dependent Manner in Non-Small Cell Lung Cancer.

Minnelide/Triptolide (TL) has recently emerged as a potent anticancer drug in non-small cell lung cancer (NSCLC).However, the precise mechanism of its action remains ambiguous.In this study, we elucidated the molecular basis Drainage and Suction Accessories for TL-induced cell death in context to p53 status.Cell death was attributed to dysfunction

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Effect of three species of host tree on the cold hardiness of overwintering larvae of Anoplophora glabripennis (Coleoptera: Cerambycidae)

The Asian long-horned beetle, Anoplophora glabripennis, is a serious destructive pest of forests throughout China as it attacks a wide range of host plants.The effect of Shelf Support host trees on the cold hardiness of A.glabripennis larvae could be the basis for predicting the performance of this forest pest on different common hosts.To evaluate

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Assessment of CareStartTM G6PD RDT for G6PD deficiency screening in newborns and malaria diagnosed subjects in the Northern Thailand

Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an inherited enzymatic disorder associated with severe neonatal hyperbilirubinemia and acute hemolysis after exposure to certain drugs or infections.The most common test for screening G6PD deficiency is fluorescent spot test which is rapid and convenient.However, fluorescent spot te

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Proposed declassification of disease categories related to sexual orientation in the International Statistical Classification of Diseases and Related Health Problems (ICD-11)

The World Health Organization is developing the 11th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-11), planned for publication in 2017.The Working Group on the Classification of Sexual Disorders and Sexual Health was charged with reviewing and making recommendations on disease categories rela

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